Welcome to the Dando Lab!
The scientific interest of Dando Lab is divided into two different projects, from neoplastic to andrological diseases.
Concerning the study of cancer features, we mainly aim at the characterization of cancer stem cells (CSCs), which play a central role in tumorigenesis, radio/chemo-resistance, development of metastases, and relapses in many types of cancer. Particular attention is paid to the study of the metabolic characteristics of these cells in ductal adenocarcinoma of the pancreas with the aim to identifying specific alterations, useful for the discovery of new early diagnostic markers and for the development of new effective therapeutic strategies.
About andrological diseases, we apply a biochemical and molecular approach to study, in an innovative way, the activation of pathways by the treatment of primary testicular and gubernacular cells with human chorionic gonadotropin and the intra-cellular alterations that characterized sets of patients affected by cryptorchidism, testicular torsion, and infertility.
Today we celebrate World Pancreatic Cancer Day to raise awareness and inform about this neoplasm. Pancreatic cancer is a big killer: silent, difficult to diagnose in a timely manner and to treat.