Publications

2021

  • Dando I, Carmona-Carmona CA, Zampieri N. Human Chorionic Gonadotropin-Mediated Induction of Breast Cancer Cell Proliferation and Differentiation. Cells. 2021 Jan 29;10(2):264. doi: 10.3390/cells10020264. PMID: 33572731. [PubMed]
  • Cavallini C, Galasso M, Pozza ED, Chignola R, Lovato O, Dando I, Romanelli MG, Krampera M, Pizzolo G, Donadelli M, Scupoli MT. Effects of CD20 antibodies and kinase inhibitors on B-cell receptor signalling and survival of chronic lymphocytic leukaemia cells. Br J Haematol. 2021 Jan;192(2):333-342. doi: 10.1111/bjh.17139. Epub 2020 Nov 20. PMID: 33216963. [PubMed]

2020

  • Forciniti S, Dalla Pozza E, Greco MR, Amaral Carvalho TM, Rolando B, Ambrosini G, Carmona-Carmona CA, Pacchiana R, Di Molfetta D, Donadelli M, Arpicco S, Palmieri M, Reshkin SJ, Dando I, Cardone RA. Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine. Int J Mol Sci. 2020 Dec 22;22(1):29. doi: 10.3390/ijms22010029. PMID: 33375106; PMCID: PMC7792955. [PubMed]
  • Sharma P, Dando I, Strippoli R, Kumar S, Somoza A, Cordani M, Tafani M. Nanomaterials for Autophagy-Related miRNA-34a Delivery in Cancer Treatment. Front Pharmacol. 2020 Jul 24;11:1141. doi: 10.3389/fphar.2020.01141. PMID: 32792960; PMCID: PMC7393066. [PubMed]
  • Ambrosini G, Dalla Pozza E, Fanelli G, Di Carlo C, Vettori A, Cannino G, Cavallini C, Carmona-Carmona CA, Brandi J, Rinalducci S, Scupoli MT, Rasola A, Cecconi D, Palmieri M, Dando I. Progressively De-Differentiated Pancreatic Cancer Cells Shift from Glycolysis to Oxidative Metabolism and Gain a Quiescent Stem State. Cells. 2020 Jun 28;9(7):1572. doi: 10.3390/cells9071572. PMID: 32605166; PMCID: PMC7408749. [PubMed]
  • Dalla Pozza E, Dando I, Pacchiana R, Liboi E, Scupoli MT, Donadelli M, Palmieri M. Regulation of succinate dehydrogenase and role of succinate in cancer. Semin Cell Dev Biol. 2020 Feb;98:4-14. doi: 10.1016/j.semcdb.2019.04.013. Epub 2019 May 1. PMID: 31039394. [PubMed]

2019

  • Dando I, Pozza ED, Ambrosini G, Torrens-Mas M, Butera G, Mullappilly N, Pacchiana R, Palmieri M, Donadelli M. Oncometabolites in cancer aggressiveness and tumour repopulation. Biol Rev Camb Philos Soc. 2019 Aug;94(4):1530-1546. doi: 10.1111/brv.12513. Epub 2019 Apr 10. PMID: 30972955. [PubMed]
  • Marengo A, Forciniti S, Dando I, Dalla Pozza E, Stella B, Tsapis N, Yagoubi N, Fanelli G, Fattal E, Heeschen C, Palmieri M, Arpicco S. Pancreatic cancer stem cell proliferation is strongly inhibited by diethyldithiocarbamate-copper complex loaded into hyaluronic acid decorated liposomes. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):61-72. doi: 10.1016/j.bbagen.2018.09.018. Epub 2018 Sep 26. PMID: 30267751. [PubMed]

2018

  • Cordani M, Butera G, Dando I, Torrens-Mas M, Butturini E, Pacchiana R, Oppici E, Cavallini C, Gasperini S, Tamassia N, Nadal-Serrano M, Coan M, Rossi D, Gaidano G, Caraglia M, Mariotto S, Spizzo R, Roca P, Oliver J, Scupoli MT, Donadelli M. Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells. Br J Cancer. 2018 Oct;119(8):994-1008. doi: 10.1038/s41416-018-0288-2. Epub 2018 Oct 15. PMID: 30318520; PMCID: PMC6203762. [PubMed]
  • Biondani G, Zeeberg K, Greco MR, Cannone S, Dando I, Dalla Pozza E, Mastrodonato M, Forciniti S, Casavola V, Palmieri M, Reshkin SJ, Cardone RA. Extracellular matrix composition modulates PDAC parenchymal and stem cell plasticity and behavior through the secretome. FEBS J. 2018 Jun;285(11):2104-2124. doi: 10.1111/febs.14471. Epub 2018 Apr 27. Erratum in: FEBS J. 2019 Sep;286(17):3504. PMID: 29660229. [PubMed]
  • Cavallini C, Chignola R, Dando I, Perbellini O, Mimiola E, Lovato O, Laudanna C, Pizzolo G, Donadelli M, Scupoli MT. Low catalase expression confers redox hypersensitivity and identifies an indolent clinical behavior in CLL. Blood. 2018 Apr 26;131(17):1942-1954. doi: 10.1182/blood-2017-08-800466. Epub 2018 Feb 21. PMID: 29467184. [PubMed]
  • Dalla Pozza E, Forciniti S, Palmieri M, Dando I. Secreted molecules inducing epithelial-to-mesenchymal transition in cancer development. Semin Cell Dev Biol. 2018 Jun;78:62-72. doi: 10.1016/j.semcdb.2017.06.027. Epub 2017 Jun 30. PMID: 28673679. [PubMed]

2017

  • Dando I, Pacchiana R, Pozza ED, Cataldo I, Bruno S, Conti P, Cordani M, Grimaldi A, Butera G, Caraglia M, Scarpa A, Palmieri M, Donadelli M. UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism. Free Radic Biol Med. 2017 Dec;113:176-189. doi: 10.1016/j.freeradbiomed.2017.09.022. Epub 2017 Sep 27. PMID: 28962872. [PubMed]
  • Brandi J, Dando I, Pozza ED, Biondani G, Jenkins R, Elliott V, Park K, Fanelli G, Zolla L, Costello E, Scarpa A, Cecconi D, Palmieri M. Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways. J Proteomics. 2017 Jan 6;150:310-322. doi: 10.1016/j.jprot.2016.10.002. Epub 2016 Oct 13. PMID: 27746256. [PubMed]

2016

  • Brandi J, Cecconi D, Cordani M, Torrens-Mas M, Pacchiana R, Dalla Pozza E, Butera G, Manfredi M, Marengo E, Oliver J, Roca P, Dando I, Donadelli M. The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition. Free Radic Biol Med. 2016 Dec;101:305-316. doi: 10.1016/j.freeradbiomed.2016.10.499. Epub 2016 Oct 27. PMID: 27989750. [PubMed]
  • Dando I, Cordani M, Donadelli M. Mutant p53 and mTOR/PKM2 regulation in cancer cells. IUBMB Life. 2016 Sep;68(9):722-6. doi: 10.1002/iub.1534. Epub 2016 Jul 7. PMID: 27385486. [PubMed]
  • Cordani M, Oppici E, Dando I, Butturini E, Dalla Pozza E, Nadal-Serrano M, Oliver J, Roca P, Mariotto S, Cellini B, Blandino G, Palmieri M, Di Agostino S, Donadelli M. Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition. Mol Oncol. 2016 Aug;10(7):1008-29. doi: 10.1016/j.molonc.2016.04.001. Epub 2016 Apr 12. PMID: 27118659; PMCID: PMC5423176. [PubMed]
  • Brandi J, Dalla Pozza E, Dando I, Biondani G, Robotti E, Jenkins R, Elliott V, Park K, Marengo E, Costello E, Scarpa A, Palmieri M, Cecconi D. Secretome protein signature of human pancreatic cancer stem-like cells. J Proteomics. 2016 Mar 16;136:1-12. doi: 10.1016/j.jprot.2016.01.017. Epub 2016 Feb 2. PMID: 26850699. [PubMed]

2015

  • Dando I, Dalla Pozza E, Biondani G, Cordani M, Palmieri M, Donadelli M. The metabolic landscape of cancer stem cells. IUBMB Life. 2015 Sep;67(9):687-93. doi: 10.1002/iub.1426. Epub 2015 Sep 4. PMID: 26337609. [PubMed]
  • Dando I, Cordani M, Dalla Pozza E, Biondani G, Donadelli M, Palmieri M. Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells. Oxid Med Cell Longev. 2015;2015:425708. doi: 10.1155/2015/425708. Epub 2015 Apr 29. PMID: 26064420; PMCID: PMC4429193. [PubMed]
  • Donadelli M, Dando I, Dalla Pozza E, Palmieri M. Mitochondrial uncoupling protein 2 and pancreatic cancer: a new potential target therapy. World J Gastroenterol. 2015 Mar 21;21(11):3232-8. doi: 10.3748/wjg.v21.i11.3232. PMID: 25805929; PMCID: PMC4363752. [PubMed]
  • Dalla Pozza E, Dando I, Biondani G, Brandi J, Costanzo C, Zoratti E, Fassan M, Boschi F, Melisi D, Cecconi D, Scupoli MT, Scarpa A, Palmieri M. Pancreatic ductal adenocarcinoma cell lines display a plastic ability to bi‑directionally convert into cancer stem cells. Int J Oncol. 2015 Mar;46(3):1099-108. doi: 10.3892/ijo.2014.2796. Epub 2014 Dec 12. PMID: 25502497. [PubMed]

2014

  • Donadelli M, Dando I, Fiorini C, Palmieri M. Regulation of miR-23b expression and its dual role on ROS production and tumour development. Cancer Lett. 2014 Jul 28;349(2):107-13. doi: 10.1016/j.canlet.2014.04.012. Epub 2014 Apr 19. PMID: 24755453. [PubMed]
  • Donadelli M, Dando I, Fiorini C, Palmieri M. UCP2, a mitochondrial protein regulated at multiple levels. Cell Mol Life Sci. 2014 Apr;71(7):1171-90. doi: 10.1007/s00018-013-1407-0. Epub 2013 Jun 27. PMID: 23807210. [PubMed]

2013

  • Arpicco S, Lerda C, Dalla Pozza E, Costanzo C, Tsapis N, Stella B, Donadelli M, Dando I, Fattal E, Cattel L, Palmieri M. Hyaluronic acid-coated liposomes for active targeting of gemcitabine. Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):373-80. doi: 10.1016/j.ejpb.2013.06.003. Epub 2013 Jun 18. PMID: 23791684. [PubMed]
  • Dando I, Donadelli M, Costanzo C, Dalla Pozza E, D’Alessandro A, Zolla L, Palmieri M. Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells. Cell Death Dis. 2013 Jun 13;4(6):e664. doi: 10.1038/cddis.2013.151. PMID: 23764845; PMCID: PMC3698539. [PubMed]
  • Brandi J, Dando I, Palmieri M, Donadelli M, Cecconi D. Comparative proteomic and phosphoproteomic profiling of pancreatic adenocarcinoma cells treated with CB1 or CB2 agonists. Electrophoresis. 2013 May;34(9-10):1359-68. doi: 10.1002/elps.201200402. Epub 2013 Apr 11. PMID: 23463621. [PubMed]
  • Dalla Pozza E, Lerda C, Costanzo C, Donadelli M, Dando I, Zoratti E, Scupoli MT, Beghelli S, Scarpa A, Fattal E, Arpicco S, Palmieri M. Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity. Biochim Biophys Acta. 2013 May;1828(5):1396-404. doi: 10.1016/j.bbamem.2013.01.020. Epub 2013 Feb 4. PMID: 23384419. [PubMed]
  • Dando I, Fiorini C, Pozza ED, Padroni C, Costanzo C, Palmieri M, Donadelli M. UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells. Biochim Biophys Acta. 2013 Mar;1833(3):672-9. doi: 10.1016/j.bbamcr.2012.10.028. Epub 2012 Nov 2. PMID: 23124112. [PubMed]
  • Fiorini C, Menegazzi M, Padroni C, Dando I, Dalla Pozza E, Gregorelli A, Costanzo C, Palmieri M, Donadelli M. Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis. Apoptosis. 2013 Mar;18(3):337-46. doi: 10.1007/s10495-012-0790-6. PMID: 23238993. [PubMed]

2012

  • Rosati A, Bersani S, Tavano F, Dalla Pozza E, De Marco M, Palmieri M, De Laurenzi V, Franco R, Scognamiglio G, Palaia R, Fontana A, di Sebastiano P, Donadelli M, Dando I, Medema JP, Dijk F, Welling L, di Mola FF, Pezzilli R, Turco MC, Scarpa A. Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival. Am J Pathol. 2012 Nov;181(5):1524-9. doi: 10.1016/j.ajpath.2012.07.016. Epub 2012 Aug 31. PMID: 22944597. [PubMed]
  • Dalla Pozza E, Fiorini C, Dando I, Menegazzi M, Sgarbossa A, Costanzo C, Palmieri M, Donadelli M. Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine. Biochim Biophys Acta. 2012 Oct;1823(10):1856-63. doi: 10.1016/j.bbamcr.2012.06.007. Epub 2012 Jun 15. PMID: 22705884. [PubMed]

2011

  • Donadelli M, Dando I, Zaniboni T, Costanzo C, Dalla Pozza E, Scupoli MT, Scarpa A, Zappavigna S, Marra M, Abbruzzese A, Bifulco M, Caraglia M, Palmieri M. Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism. Cell Death Dis. 2011 Apr 28;2(4):e152. doi: 10.1038/cddis.2011.36. PMID: 21525939; PMCID: PMC3122066. [PubMed]
  • Dalla Pozza E, Donadelli M, Costanzo C, Zaniboni T, Dando I, Franchini M, Arpicco S, Scarpa A, Palmieri M. Gemcitabine response in pancreatic adenocarcinoma cells is synergistically enhanced by dithiocarbamate derivatives. Free Radic Biol Med. 2011 Apr 15;50(8):926-33. doi: 10.1016/j.freeradbiomed.2011.01.001. Epub 2011 Jan 12. PMID: 21236335. [PubMed]

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